-50%

Coveram 5mg 5mg B 30 on Sale

Original price was: $13.00.Current price is: $6.50.
0 reviews
21 people are viewing this right now
Estimated Delivery:
15 - 22 Mar, 2025
Trust Badge
Guaranteed safe & secure checkout

Description

Indications:

Perindopril arginine + Amlodipine besilate (COVERAM) is indicated as substitution therapy for treatment of essential hypertension and or stable coronary artery disease, in patients already controlled with perindopril and amlodipine given concurrently at the same dose level.

Active Ingredient:

Perindopril arginine 5mg, Amlodipine 5mg

Dosage Direction for Use

Posology: Oral route.

  • One tablet per day as a single dose, preferably to be taken in the morning and before a meal.
  • The fixed dose combination is not suitable for initial therapy.
  • If a change of posology is required, the dose of Perindopril arginine + Amlodipine besilate (COVERAM) could be modified or individual titration with free combination may be considered.
    • Special populations: Renal impairment and elderly: Elimination of perindoprilat is decreased in the elderly and in patients with renal failure. Therefore, the usual medical follow-up will include frequent monitoring of creatinine and potassium.
      Perindopril arginine + Amlodipine besilate (COVERAM) can be administered in patients with Clcr ≥60 mL min, and is not suitable for patients with Clcr < 60 mL min. In these patients, an individual dose titration with the monocomponents is recommended.
      Amlodipine used at similar doses in elderly or younger patients is equally well tolerated. Normal dosage regimens are recommended in the elderly, but increase of the dosage should take place with care. Changes in amlodipine plasma concentrations are not correlated with degree of renal impairment. Amlodipine is not dialyzable.


      Hepatic impairment: Dosage recommendations have not been established in patients with mild to moderate hepatic impairment; therefore dose selection should be cautious and should start at the lower end of the dosing range. To find the optimal starting dose and maintenance dose of patients with hepatic impairment, the patients should be individually titrated using the free combination of amlodipine and perindopril. The pharmacokinetics of amlodipine have not been studied in severe hepatic impairment. Amlodipine should be initiated at the lowest dose and titrated slowly in patients with severe hepatic impairment.


      Pediatric population: Perindopril arginine + Amlodipine besilate (COVERAM) should not be used in children and adolescents as the efficacy and tolerability of perindopril and amlodipine, in combination, have not been established in children and adolescents.

      Related products

      zoomwovenus.shop © 2025 All Rights Reserved

      Select the fields to be shown. Others will be hidden. Drag and drop to rearrange the order.
      • Image
      • SKU
      • Rating
      • Price
      • Stock
      • Description
      • Weight
      • Dimensions
      • Additional information
      • Add to cart
      Click outside to hide the comparison bar
      Compare